Our News
Expert Orthopaedic Insights
Evidence-based articles from MSK specialists
Explore our latest guidance on joint health, sports injuries and personalised treatment pathways. All content is written and reviewed by our consultant specialists.

Our News
Evidence-based articles from MSK specialists
Explore our latest guidance on joint health, sports injuries and personalised treatment pathways. All content is written and reviewed by our consultant specialists.

ChondroFiller, an injectable collagen scaffold that recruits the patient's own progenitor cells, qualifies candidates with MRI-confirmed structural cartilage damage and failed conservative treatment, not symptom severity.

Misalignment accelerates cartilage damage by concentrating load on an already injured zone; osteotomy redirects this load, deferring total knee replacement by years, whilst creating conditions where cartilage repair grafts can integrate and survive.

An osteochondral lesion of the talus (cartilage and bone damage) affects an estimated 50–70% of significant ankle sprains but is missed on initial X-ray in roughly 50% of cases, often delaying diagnosis by years.

Microfracture fails in 97% of cases for ankle cartilage defects larger than 15mm diameter; MACI, a two-stage procedure using cultured chondrocytes on a collagen scaffold, addresses lesions at and beyond this threshold.

ChondroFiller provides a temporary biological scaffold that recruits the patient's own progenitor cells to rebuild cartilage defects; fully resorbed within twelve to twenty-four months, it is replaced entirely by the patient's own organised repair tissue.

Quantitative MRI and markerless motion analysis are used to spot cartilage, meniscus and loading changes before obvious joint wear appears. By tracking tissue quality and gait over set review points, clinicians can decide earlier whether a knee should be re...
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