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Expert Orthopaedic Insights

Evidence-based articles from MSK specialists

Explore our latest guidance on joint health, sports injuries and personalised treatment pathways. All content is written and reviewed by our consultant specialists.

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ChondroFiller02 Jul 2026

ChondroFiller safety across 19,000 real-world treatments

Across 19,000+ real-world treatments spanning eight joint types, ChondroFiller® liquid has produced zero serious adverse device effects.

John Davies

ACI / MACI / STACI02 Jul 2026

Mosaicplasty or ACI for a focal knee cartilage defect

For focal knee cartilage defects, size determines the technique. Defects under 2 cm² on the femoral condyle suit single-stage mosaicplasty; larger lesions and patellar involvement favour ACI, which has better long-term outcomes.

John Davies

Cartilage Repair01 Jul 2026

How defect size shapes knee cartilage repair options

Cartilage defect size determines which repair is appropriate and its durability. Microfracture for lesions under 2 cm² produces tissue degrading within two to three years; autografts for 2–4 cm² last considerably longer; larger defects require donor or cult...

John Davies

ChondroFiller01 Jul 2026

ChondroFiller injection cost in the UK versus Germany

ChondroFiller, a collagen scaffold for cartilage regeneration, is delivered by ultrasound-guided outpatient injection in UK clinics (£3,000–£8,000) rather than arthroscopic surgery in Germany (€3,800–€10,000).

John Davies

ChondroFiller30 Jun 2026

ChondroFiller Injection for Talar Osteochondral Lesions

Osteochondral lesions of the talus cause cartilage damage that cannot repair itself due to poor blood supply. ChondroFiller, an injected collagen scaffold, acts as a structural matrix, recruiting progenitor cells to differentiate and rebuild tissue over 12–...

John Davies

AMIC30 Jun 2026

AMIC vs MACI for focal knee defects

AMIC repairs focal knee cartilage defects of 2–4 cm² in a single operation using bone-marrow stimulation beneath a collagen membrane; MACI, a two-stage procedure using laboratory-expanded chondrocytes, is preferred for defects above roughly 3–5 cm².

John Davies

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