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Expert Orthopaedic Insights

Evidence-based articles from MSK specialists

Explore our latest guidance on joint health, sports injuries and personalised treatment pathways. All content is written and reviewed by our consultant specialists.

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ChondroFiller02 Sept 2026

ChondroFiller injection outcomes at one to three years

Functional gains of 30 points from ChondroFiller are sustained to three years and consolidate progressively as collagen recruits and organises repair tissue.

John Davies

cartilage damage02 Sept 2026

Do I Have Cartilage Damage or Knee Arthritis?

Focal cartilage damage and osteoarthritis produce identical knee pain and stiffness, yet call for opposite treatments—one potentially repairable, the other managed through load control—and only MRI imaging reliably distinguishes them.

John Davies

OATS / Mosaicplasty02 Sept 2026

OATS surgery for ankle osteochondral defects

Ankle lesions larger than 15 mm fail with marrow stimulation; OATS uses hyaline cartilage from the patient's own knee to restore the joint surface in a single operation, with functional gains durable over seven years.

John Davies

ChondroFiller01 Sept 2026

ChondroFiller as a Knee Replacement Alternative

ChondroFiller is a liquid collagen that self-polymerises into a three-dimensional scaffold to recruit the joint's own repair cells into damaged cartilage, but qualifies only where conservative treatments have failed and structural damage is MRI-confirmed.

John Davies

knee pain01 Sept 2026

Knee Pain When the MRI Looks Mild

MRI scans explain only 28% of knee pain variation because cartilage lacks pain fibres. Pain originates instead in the subchondral bone beneath, which is densely innervated with nociceptive nerve endings.

John Davies

ACI / MACI / STACI01 Sept 2026

Ten-year ACI outcomes for knee cartilage repair

Ten-year follow-up of MACI patients found 92% satisfaction with pain relief and 9.3% graft failure; improvement consolidates by year two then remains stable — contrasting with microfracture, which deteriorates after year two.

John Davies

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