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Expert Orthopaedic Insights

Evidence-based articles from MSK specialists

Explore our latest guidance on joint health, sports injuries and personalised treatment pathways. All content is written and reviewed by our consultant specialists.

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ChondroFiller19 Jun 2026

ChondroFiller injection for hip cartilage defects

Injected under ultrasound, ChondroFiller polymerises at body temperature into a collagen matrix that recruits the patient's own cells to remodel into repair tissue over three to six months—a mechanism distinct from steroids and hyaluronic acid, which manage...

John Davies

ACI / MACI / STACI19 Jun 2026

MACI for Patellofemoral Cartilage Damage

MACI for patellofemoral cartilage requires focal, full-thickness loss with intact subchondral bone, defects of 2–10 cm², and corrected patellar alignment; uncorrected tracking concentrates asymmetric stress on the repair, a principal cause of implant failure.

John Davies

ChondroFiller18 Jun 2026

ChondroFiller injection as first-line knee cartilage care

An injectable collagen scaffold recruits the patient's own cells to regenerate focal cartilage, achieving outcomes equivalent to surgical implantation within 12 months as a single outpatient appointment without theatre or general anaesthetic.

John Davies

OCA18 Jun 2026

Fresh osteochondral allograft for ankle lesions

Microfracture produces only a 3% success rate for ankle osteochondral lesions exceeding 15 mm in diameter. Fresh osteochondral allograft replaces cartilage and bone together and is indicated for lesions too large or structurally complex for simpler repairs ...

John Davies

ChondroFiller17 Jun 2026

ChondroFiller injection for thumb base cartilage damage

ChondroFiller is an injectable collagen scaffold that self-gels into focal cartilage defects at the thumb base, recruiting the patient's own progenitor cells to rebuild damaged tissue — treating the gap between pain-relief injections and joint replacement.

John Davies

ACI / MACI / STACI17 Jun 2026

ACI with HTO for medial knee cartilage repair

Varus malalignment creates a mechanical environment that undermines cartilage repair; combined ACI implantation and corrective osteotomy address both the tissue damage and the load concentration that drives it.

John Davies

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