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Expert Orthopaedic Insights

Evidence-based articles from MSK specialists

Explore our latest guidance on joint health, sports injuries and personalised treatment pathways. All content is written and reviewed by our consultant specialists.

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Who qualifies for MACI knee cartilage repair
ACI / MACI / STACI25 Jun 2026

Who qualifies for MACI knee cartilage repair

MACI repairs deep cartilage defects—Grade III or IV, at least 2 cm²—only when the knee's ligaments, alignment, and meniscus can support the months-long graft maturation in a mechanically stable joint.

John Davies
Can cartilage repair delay knee replacement
Cartilage Repair24 Jun 2026

Can cartilage repair delay knee replacement

Cartilage repair can delay or avoid knee replacement for focal defects in otherwise healthy joints, but diffuse osteoarthritis — where the whole joint surface has worn — falls outside the scope of these procedures.

John Davies
ChondroFiller vs Arthrosamid for knee cartilage loss
ChondroFiller24 Jun 2026

ChondroFiller vs Arthrosamid for knee cartilage loss

ChondroFiller and Arthrosamid are not competing treatments — they address entirely different pathologies. ChondroFiller is a collagen scaffold that recruits the body's own cells to repair focal cartilage defects; Arthrosamid is a hydrogel that cushions the ...

John Davies
ChondroFiller safety after 19,000 injections
ChondroFiller23 Jun 2026

ChondroFiller safety after 19,000 injections

In 19,000-plus ultrasound-guided injections tracked in regulatory data, ChondroFiller showed zero serious adverse effects and a 3–8% reoperation rate, compared with 41% for surgical microfracture.

John Davies
MACI Knee Recovery: Week One to Return to Sport
ACI / MACI / STACI23 Jun 2026

MACI Knee Recovery: Week One to Return to Sport

MACI recovery spans nine to twelve months because cartilage repair tissue must mature through cellular remodelling stages that cannot be safely compressed—a timeline driven by biology, not bureaucracy.

John Davies
Choosing the right knee cartilage repair
Cartilage Repair22 Jun 2026

Choosing the right knee cartilage repair

Modern knee cartilage repairs produce hyaline or hyaline-like cartilage, whereas microfracture—the older standard—produces fibrocartilage (scar-like tissue) that typically deteriorates within two to three years and requires reoperation in 41% of cases.

John Davies

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