Our News
Expert Orthopaedic Insights
Evidence-based articles from MSK specialists
Explore our latest guidance on joint health, sports injuries and personalised treatment pathways. All content is written and reviewed by our consultant specialists.

Our News
Evidence-based articles from MSK specialists
Explore our latest guidance on joint health, sports injuries and personalised treatment pathways. All content is written and reviewed by our consultant specialists.

MACI repairs deep cartilage defects—Grade III or IV, at least 2 cm²—only when the knee's ligaments, alignment, and meniscus can support the months-long graft maturation in a mechanically stable joint.

Cartilage repair can delay or avoid knee replacement for focal defects in otherwise healthy joints, but diffuse osteoarthritis — where the whole joint surface has worn — falls outside the scope of these procedures.

ChondroFiller and Arthrosamid are not competing treatments — they address entirely different pathologies. ChondroFiller is a collagen scaffold that recruits the body's own cells to repair focal cartilage defects; Arthrosamid is a hydrogel that cushions the ...

In 19,000-plus ultrasound-guided injections tracked in regulatory data, ChondroFiller showed zero serious adverse effects and a 3–8% reoperation rate, compared with 41% for surgical microfracture.

MACI recovery spans nine to twelve months because cartilage repair tissue must mature through cellular remodelling stages that cannot be safely compressed—a timeline driven by biology, not bureaucracy.

Modern knee cartilage repairs produce hyaline or hyaline-like cartilage, whereas microfracture—the older standard—produces fibrocartilage (scar-like tissue) that typically deteriorates within two to three years and requires reoperation in 41% of cases.
Our team includes some of the UK’s leading musculoskeletal experts, with years of experience in orthopaedic care, sports medicine, and regenerative treatments. When you choose MSK Doctors, you’re in the hands of specialists who are passionate about helping you recover.
Whether it’s a consultation, treatment, or a second opinion, our team is here to help. Get in touch today and let’s start your journey to recovery.