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Expert Orthopaedic Insights

Evidence-based articles from MSK specialists

Explore our latest guidance on joint health, sports injuries and personalised treatment pathways. All content is written and reviewed by our consultant specialists.

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ChondroFiller30 Jun 2026

ChondroFiller Injection for Talar Osteochondral Lesions

Osteochondral lesions of the talus cause cartilage damage that cannot repair itself due to poor blood supply. ChondroFiller, an injected collagen scaffold, acts as a structural matrix, recruiting progenitor cells to differentiate and rebuild tissue over 12–...

John Davies

AMIC30 Jun 2026

AMIC vs MACI for focal knee defects

AMIC repairs focal knee cartilage defects of 2–4 cm² in a single operation using bone-marrow stimulation beneath a collagen membrane; MACI, a two-stage procedure using laboratory-expanded chondrocytes, is preferred for defects above roughly 3–5 cm².

John Davies

ChondroFiller29 Jun 2026

ChondroFiller results at two years for focal knee defects

Across four published cohorts, ChondroFiller achieved consistent 30-point improvements on the IKDC knee-function scale for focal cartilage defects, with functional gains sustained beyond twelve months.

John Davies

ACI / MACI / STACI29 Jun 2026

MACI cartilage durability at ten years

MACI cartilage repair preserves the native knee in 88–93% of patients at ten years, with 92% reporting satisfaction with pain relief and graft survival at 97.2%, per two 2024 prospective studies.

John Davies

ChondroFiller28 Jun 2026

Why ultrasound guidance matters for hip ChondroFiller

ChondroFiller is a collagen gel that self-gels within minutes, triggering cell recruitment inside hip cartilage defects. Because the gel sets irreversibly on contact, its placement inside the focal lesion must be confirmed via ultrasound before injection—wi...

John Davies

OATS / Mosaicplasty28 Jun 2026

OATS vs Microfracture at 10 Years for Active Patients

At ten years, OATS fails in 14% of young athletes versus 38% for microfracture, because transplanted hyaline cartilage remains stable under loading whilst the fibrocartilage that microfracture generates progressively degrades.

John Davies

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