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Expert Orthopaedic Insights

Evidence-based articles from MSK specialists

Explore our latest guidance on joint health, sports injuries and personalised treatment pathways. All content is written and reviewed by our consultant specialists.

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ChondroFiller07 Jul 2026

Is ChondroFiller available on the NHS

ChondroFiller is an acellular collagen scaffold that recruits the body's own cells to repair focal cartilage damage; European data shows 70–85% of patients report meaningful symptom relief, with outcomes comparable to NHS procedures like ACI but without the...

John Davies

OATS / Mosaicplasty07 Jul 2026

How Defect Size Decides Between OATS and MACI

Cartilage defect size is the primary decision driver: lesions under 2 cm² suit OATS, the 2–4 cm² band produces equivalent outcomes with either approach, and defects above 4 cm² favour MACI. Bone loss or staging preference can alter the recommendation.

John Davies

ChondroFiller06 Jul 2026

ChondroFiller vs corticosteroid for knee pain

Corticosteroids suppress inflammation in diffuse osteoarthritis, providing relief within days; ChondroFiller targets focal cartilage defects with collagen scaffolds that support tissue repair over six to twelve months. They address structurally distinct pro...

John Davies

Joint Preservation06 Jul 2026

Can an osteotomy delay or avoid knee replacement?

Osteotomy shifts the weight-bearing axis to spare damaged cartilage, enabling 79% of well-selected patients to avoid knee replacement at ten years—though survival declines to 44% by twenty.

John Davies

ChondroFiller05 Jul 2026

ChondroFiller vs Arthrosamid for knee pain

ChondroFiller is a collagen scaffold injected into cartilage defects to regenerate cartilage-like tissue, while Arthrosamid is a permanent hydrogel that cushions the joint lining; the appropriate treatment depends on MRI findings, not patient preference.

John Davies

ACI / MACI / STACI05 Jul 2026

MACI vs ACI for Knee Cartilage Repair

MACI refines ACI, a 1980s technique for focal cartilage defects: both grow a patient's cells in the laboratory before implantation, and one-year trial evidence finds them equivalent, with durability sustained beyond a decade.

John Davies

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