Arthrosamid Injection for Knee Osteoarthritis: Effectiveness, Side Effects & Cost

Key Takeaways

• Arthrosamid injection contains 97.5% non-pyrogenic water and 2.5% cross-linked polyacrylamide, acting as a cushioning agent within the joint - ideal for patients with knee osteoarthritis (OA). 

• Clinical studies show a single Arthrosamid injection can last up to 3 years, with significant improvements in pain and joint function.

• Some of the side effects of Arthrosamid injection are temporary swelling or discomfort at the injection site. 

• The average cost of Arthrosamid injections is up to £2,995 for a single knee joint and around £5,000 for both knee joints.

• MSK Doctors provides comprehensive same-day care, including AI motion analysis and MRI scans, ensuring precise treatment delivery for knee OA.

Intro to Arthrosamid Injections 

What is Arthrosamid

Arthrosamid is an innovative treatment that targets knee osteoarthritis (OA), a common condition affecting millions worldwide. Also known as intra-articular polyacrylamide hydrogel (iPAAG), it’s an intra-articular injection, meaning it's administered directly into the joint space. 

The primary aim of Arthrosamid is to alleviate pain and improve joint function by acting as a cushion within the knee. Unlike some treatments that require frequent administration, Arthrosamid provides long-lasting relief (up to 3 years) with just a single injection.

MSK Doctors: Expert Musculoskeletal Care Without the Wait

At MSK Doctors, we offer cutting-edge musculoskeletal (MSK) care with no need for GP referrals. Our team of leading orthopedic consultants specializes in sports injuries, joint pain, and advanced regenerative treatments, including SPAIRE Hip, BIKINI Hip, and Arthrosamid injections. We use a state-of-the-art musculoskeletal AI platform to gain valuable insights into movement patterns, helping us optimize treatment plans for better outcomes. 

With a 5-star Google rating, a comprehensive specialist directory to help you find the right expert, and a patient-centric approach, we’re here to empower you on your health journey. We also provide resources like downloadable materials, exercise guides, and self-care tips to support your recovery and well-being.

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Components and Composition

The uniqueness of Arthrosamid lies in its composition - 97.5% non-pyrogenic water and 2.5% cross-linked polyacrylamide. This composition allows it to integrate seamlessly with the synovial tissue in the knee, providing a cushioning effect that reduces friction and wear on the joint. 

Since the majority of the injection is water, it helps in creating a gel-like substance that provides the cushioning effect within the joint. The remaining 2.5% cross-linked polyacrylamide forms a three-dimensional honeycomb structure that serves as a scaffold for the synovial membrane in knee joints to regenerate (image courtesy of Arthrosamid). All this contributes to the durability and longevity of the treatment

This unique combination allows Arthrosamid to function differently than other treatments. While hyaluronic acid injections, for example, primarily act as lubricants, Arthrosamid becomes a physical part of the joint's soft tissue. This cushions the joint and reduces pain and stiffness - leading to improved mobility and quality of life.

How It Works

When Arthrosamid is injected into the knee, it integrates into the synovial tissue, forming a cushion that absorbs shocks and reduces friction between the bones. This cushioning effect is the one that will reduce OA symptoms. By minimizing friction, Arthrosamid also helps to decrease pain and improve joint movement.

Also, because the hydrogel doesn’t degrade, it provides long-term relief, unlike other treatments that may require frequent re-administration. For example, Synvisc-One needs 3 injections to provide only 6 months of knee OA pain relief while Arthrosamid only needs one 6 ml injection for up to 3 years of pain relief. 

This means fewer visits to the doctor and more time enjoying activities you love. The sustained effect of Arthrosamid makes it a convenient and effective option for those struggling with knee osteoarthritis.

Effectiveness in Knee Osteoarthritis

Pain Relief Duration

Many patients report a significant reduction in pain within days of receiving an Arthrosamid injection, with the effects lasting for several months. This prolonged relief is attributed to the hydrogel's ability to integrate with the joint tissue, providing a stable and lasting cushion.

“I couldn’t believe how quick the procedure was, with very little discomfort and limited downtime. I was able to drive immediately. Pain can be really draining emotionally. Now, thanks to Arthrosamid, I feel more able to do the things I love with less pain of it. I’m very glad I gave it a try.” – Sharron Davies MBE, Olympic Swimmer

In an NHS clinical study, Arthrosamid has demonstrated effectiveness in reducing pain for up to 3 years after a single injection - which is particularly beneficial for those who have not found relief for knee pain with other treatments.

Mobility Improvements

As the gel cushions the joint, it allows for smoother movement and reduces stiffness, which can be particularly beneficial if you’ve experienced a decline in mobility due to OA.

In fact, patients often find that they can return to activities they once enjoyed, whether it's walking, cycling, or even dancing - which can have a profound impact on both physical and mental well-being.

Clinical Efficacy

In addition to the NHS research above, numerous other studies demonstrated the safety and efficacy of Arthrosamid in treating knee OA. Here’s a summary of a few of them: 

• 52-Week Prospective Study: Found significant improvements in knee OA symptoms after 52 weeks. 

• 6-Month Prospective Study: Confirmed Arthrosamid’s effectiveness in treating knee OA over a 6-month period. 

• Reduction in Patellofemoral Bone Marrow Lesions: Showed that a single intra-articular injection of Arthrosamid reduced patellofemoral bone marrow lesions. 

Comparing Effectiveness with Other Treatments

Arthrosamid vs. Hyaluronic Acid

Hyaluronic acid injections, which have been a popular choice for managing knee OA, work by supplementing the natural synovial fluid in the joint, providing lubrication and reducing friction. However, the effects of hyaluronic acid are often short-lived, requiring repeated injections every few months.

Arthrosamid is a more durable solution. Its unique hydrogel composition not only lubricates the joint but also integrates with the soft tissue - providing a cushioning effect that lasts longer. 

Comparative Long-term Benefits

Arthrosamid hydrogel is non-degradable, which means that patients experience sustained relief without the need for frequent re-administration - not the case with other treatments like corticosteroid injections, which may offer immediate relief but often require repeated doses due to their temporary effects.

Surgical Alternatives and Considerations

For some individuals with severe knee OA, surgery may be considered as a last resort. Procedures such as knee arthroscopy or total knee replacement can offer significant relief but come with risks and a lengthy recovery period.

Arthrosamid is a minimally invasive alternative that can delay or even remove the need for surgery completely, by providing effective pain relief and improving joint function. This is particularly beneficial if you’re not an ideal candidate for surgery due to age or underlying health conditions.

Arthrosamid Side Effects

Common Side Effects

Like any medical treatment, Arthrosamid may have side effects, although they are generally mild and typically subside on their own within a few days:

• Pain at the injection site

• Swelling around the injection site

• Knee swelling that may last for 4 to 6 weeks

• Feeling of fullness or distention in the knee joint

Severe Yet Rare Side Effects

On the other hand, other severe yet rare side effects are: 

• Baker’s cyst (fluid-filled growth behind the knee).

• Allergic reactions

Discuss any concerns with your healthcare provider, who can provide guidance and ensure that the treatment is suitable for your specific needs.

Arthrosamid Injection Cost

Normal Cost

The cost of Arthrosamid injections can vary - with the average cost reaching up to £2,995 for a single knee joint and approximately £5,000 for both knees. In some severe cases, you may require a top-up dosage which comes to about £2,300 for one and £4,300 for two knee joints. 

Factors Affecting Cost

This price can fluctuate based on several factors: 

• The severity of knee OA condition

• The dosage required

• The clinic's location

• The healthcare provider's expertise

• The Arthrosamid manufacturer

Additional expenses, such as lab tests, medical supplies, and MRI or ultrasound scans for needle guidance, may also contribute to the overall cost. 

The good news is that some clinics may offer package deals that include a consultation and follow-up. While Arthrosamid may seem expensive, it’s a single-injection treatment that could potentially save money in the long run, compared to therapies requiring multiple doses. 

Your Investment in Long-Term Joint Health

While the initial cost ranges from £2,995 for a single knee to £5,000 for both knees, Arthrosamid’s long-lasting effects make it a cost-effective solution compared to treatments requiring frequent re-administration.

At MSK Doctors, we've seen firsthand how Arthrosamid transforms our patients' lives, from Olympic athletes like Sharron Davies MBE to individuals seeking to return to their daily activities without pain. Our comprehensive approach combines cutting-edge AI motion analysis, same-day MRI scans, and expert treatment delivery by leading specialists like Professor Paul Lee.

The results speak for themselves: clinical studies show significant pain relief lasting up to three years from a single injection. This extended relief period, coupled with Arthrosamid's unique ability to integrate with your joint tissue, means fewer clinic visits and more time doing what you love.

Why wait in GP referral queues when you can access immediate, expert care? Book your consultation with MSK Doctors today and join the thousands who've discovered the benefits of this innovative treatment. Let us help you make an informed decision about your joint health.

Frequently Asked Questions (FAQ)

What is the procedure for Arthrosamid injection?

The Arthrosamid injection is a straightforward procedure performed in a clinical setting. After cleaning the injection site, the healthcare provider administers the hydrogel directly into the knee joint using a fine needle. The process is quick, typically taking only a few minutes, and patients can usually resume normal activities shortly afterward.

How quickly can I expect results?

Many patients experience noticeable pain relief within days of receiving the Arthrosamid injection. The cushioning effect of the hydrogel reduces joint friction, leading to decreased pain and improved mobility. While individual results may vary, the majority of patients report significant improvements within the first week.

What are the common side effects of Arthrosamid?

Most side effects are mild and temporary, including slight pain or swelling at the injection site, typically resolving within a few days to weeks.

What makes Arthrosamid a cost-effective choice for knee OA treatment?

While the initial cost is £2,995-£5,000, a single injection can last up to three years, which means you won’t need frequent treatments - compared to alternatives like hyaluronic acid injections.

What sets MSK Doctors apart in providing Arthrosamid treatment?

MSK Doctors has same-day comprehensive care with no GP referral needed, including AI motion analysis, MRI scans, and treatment by leading specialists like Professor Paul Lee, all backed by a 5-star rating.