Conservative Management for Delayed Unions and Non-Unions (LIPUS & PEMF)

Tanvi Verma
Tanvi Verma
Published at: 7/1/2025

Bone healing is a complex process that doesn’t always follow a predictable path. In some cases, fractures may not heal as expected, resulting in delayed unions or non-unions—conditions where the bone takes significantly longer to heal or fails to heal entirely. While surgical intervention is often considered for such cases, conservative management techniques, such as Low-Intensity Pulsed Ultrasound (LIPUS) and Pulsed Electromagnetic Field (PEMF) therapy, offer promising non-invasive solutions.

Understanding Delayed Unions and Non-Unions

A delayed union occurs when a fracture takes longer than the usual timeframe to heal but still shows potential for recovery. A non-union, on the other hand, is a more severe case where there is no progress in bone healing, and the fracture remains unhealed for an extended period. These complications can arise due to various factors, including inadequate blood supply, poor fracture stability, infection, or underlying conditions like osteoporosis.

Traditionally, managing these complications involves surgical intervention such as bone grafting or internal fixation. However, these methods come with their own risks and extended recovery periods. For patients seeking a non-invasive alternative, LIPUS and PEMF therapy are emerging as effective options that promote bone healing without the need for surgery.

LIPUS: A Non-Invasive Solution for Bone Stimulation

Low-Intensity Pulsed Ultrasound (LIPUS) is a therapeutic technology designed to stimulate bone healing using low-frequency sound waves. This technique is particularly effective for delayed unions and non-unions, as it enhances the biological processes necessary for bone regeneration. LIPUS therapy works by:

  • Stimulating cellular activity: LIPUS delivers mechanical ultrasound waves to the fracture site, which enhances the activity of osteoblasts (bone-forming cells) and other cells involved in bone healing.
  • Increasing vascularisation: The therapy promotes blood flow to the fracture site, improving nutrient and oxygen delivery, which are critical for bone repair.
  • Accelerating callus formation: By stimulating the cells responsible for bone formation, LIPUS enhances the development of the callus (new bone tissue) at the fracture site, helping to stabilise the bone and promote healing.

Clinical studies have demonstrated the efficacy of LIPUS in reducing healing time and improving outcomes for patients with delayed unions or non-unions. Igea Medical’s LIPUS devices are specifically designed for ease of use, allowing patients to receive treatment at home, which enhances compliance and maximises the therapy’s effectiveness.

PEMF Therapy: Enhancing Bone Healing Through Electromagnetic Fields

Pulsed Electromagnetic Field (PEMF) therapy is another innovative, non-invasive treatment option for managing delayed unions and non-unions. By applying electromagnetic pulses to the fracture site, PEMF stimulates cellular processes that are essential for bone healing. The technology operates by:

  • Boosting osteoblast function: PEMF increases the activity and proliferation of osteoblasts, enhancing new bone formation and helping to close the gap at the fracture site.
  • Improving blood circulation: Like LIPUS, PEMF enhances microcirculation, which is vital for delivering nutrients and oxygen to the fracture, supporting the body’s natural healing process.
  • Modulating inflammatory responses: PEMF therapy helps regulate inflammation, reducing swelling and pain, which are common in cases of delayed union or non-union.

The advantage of PEMF therapy is its ability to penetrate deep into the tissues, making it effective even in complex fractures or areas with poor vascularisation. Igea Medical’s PEMF devices provide targeted treatment options that can be used home settings, giving patients flexibility and ensuring they receive consistent, effective therapy.

Comparing LIPUS and PEMF: Choosing the Right Approach

Both LIPUS and PEMF have proven effective in promoting bone healing, but they work through different mechanisms. LIPUS uses mechanical waves to directly stimulate cellular processes and blood flow, while PEMF employs electromagnetic fields to enhance cellular function and modulate inflammation. Deciding which therapy is suitable for a patient depends on several factors, including:

  • Type of fracture: For fractures with limited blood supply, PEMF’s ability to penetrate deep tissues and stimulate vascularisation may be particularly beneficial.
  • Patient’s lifestyle and preferences: Both therapies offer home-use devices, such as those developed by Igea Medical, providing convenience and flexibility. Patients may choose a therapy based on comfort and ease of use.
  • Clinical condition: In some cases, In some cases, if an inflammation is in place together with a fracture, then PEMF would be the most comprehensive, because it exerts both an osteogenic and an anti-inflammatory effect.

Igea Medical: Leading the Way in Non-Invasive Bone Healing Solutions

Igea Medical is a pioneer in developing cutting-edge LIPUS and PEMF devices designed specifically for the conservative management of delayed unions and non-unions. Their products are engineered for ease of use, portability, and clinical effectiveness, making them an ideal choice for both patients and healthcare professionals seeking non-surgical solutions.

Igea Medical’s LIPUS and PEMF devices are clinically validated and have shown to significantly reduce healing times, enhance bone integration, and improve patient outcomes. By providing home-use devices, Igea Medical ensures that patients receive consistent and reliable therapy, which is crucial for successful bone healing.

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